Merck
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Biomarker & Metabolite Standards

hormones and amino acids reference standards for biomarker analysis and metabolomics

Metabolomics is the study of chemical processes occurring within a biological system involving small molecules, called metabolites, as substrates, intermediates, and products.

We offer a broad range of analytical standards suitable for mass spectrometry-based metabolomics and biomarker testing applications. These applications include metabolic profiling, fingerprinting, clinical and diagnostic testing, target analysis for the identification of novel biomarkers of clinical relevance, pharmaceutical research of disease targets, and endocrinology. Our metabolomics and biomarker analytical standards include endogenous compounds of clinical significance such as DNA/RNA oligos; metabolites of‒ amino acids, lipids, carbohydrates, bile acids, and vitamin D; catecholamines and neurotransmitters; and male, female, neonatal, and thyroid hormones.



Hormones

Hormones are signaling molecules produced by the multicellular organisms. Our broad range of hormones includes Cerilliant® certified reference material (CRMs) solutions and analytical standards of the brand VETRANAL® for the analysis of hormone residues in food products. The standards are available in both the neat and solution form and are HPLC and GC compatible.

Amino Acid Metabolites

Our range of amino acid metabolites includes a series of certified reference materials (CRMs) solutions and analytical standards for metabolomic studies including a big selection of acylglycines and acylcarnitines.

Hydroxyvitamin D

Hydroxyvitamin D is a very stable metabolite of vitamin D. It is universally used as a marker to clinically determine the vitamin D levels in the blood. Our range of 25-hydroxy vitamin D standards offers certified reference material solutions in the native as well as isotope labeled form.

Catecholamines and Biogenic Amines

Catecholamines are amines produced by the adrenal glands and function as hormones as well as neurotransmitters. Examples of catecholamines include dopamine, epinephrine (adrenaline), and norepinephrine (noradrenaline). All catecholamines are derived from the amino acid L-tyrosine. Catecholamine levels in urine can be an indicator of certain illnesses. We offer a variety of certified reference materials solutions of catecholamine metabolites. The CRMs are available as both the single- and multi- component solutions.



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