方案
98%
表单
solid
mp
>300 °C (lit.)
溶解性
soluble 50 mg/mL, clear, colorless to faintly yellow (DMF:MeOH(2:1))
官能团
phenyl
SMILES字符串
Oc1ccc(cc1)C2(NC(=O)NC2=O)c3ccccc3
InChI
1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)
InChI key
XEEDURHPFVXALT-UHFFFAOYSA-N
一般描述
5-(4-Hydroxyphenyl)-5-phenylhydantoin is the major metabolite of phenytoin[1].
应用
5-(4-Hydroxyphenyl)-5-phenylhydantoin was used in enantiomeric separation of chiral pharmaceuticals using a teicoplanin chiral stationary phase by aqueous and non-aqueous packed capillary electrochromatography[2]. It was used as internal standard in determination of phenylbutazone and its metabolite oxyphenbutazone in human plasma by GLC[3].
Reactant for activation of hydroxylated metabolites of carbamazepine and phenytoin
Used in studies investigating
Transport across the human placenta barrier
Effects on cellular glucose transport
Used in studies investigating
Transport across the human placenta barrier
Effects on cellular glucose transport
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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