方案
98%
表单
powder
mp
218-220 °C (lit.)
SMILES字符串
O=C1CNC(=O)N1
InChI
1S/C3H4N2O2/c6-2-1-4-3(7)5-2/h1H2,(H2,4,5,6,7)
InChI key
WJRBRSLFGCUECM-UHFFFAOYSA-N
正在寻找类似产品? 访问 产品对比指南
应用
本产品已被用作底物（在 40℃ 和 pH 9.0 下），以测定红小豆提取物中的 D -海因酶活性。
用于合成以下物质的反应物：
抗癌药物 N-苄基无赖氨酸视蛋白类似物
D-谷氨酸基抑制剂
抗糖尿病铬-2,4-噻唑烷二酮类
具有脑渗透性的GSK-3β抑制剂
作为 15-PGDH 抑制剂的噻唑烷二酮衍生物
放射增敏剂
抗癌药物 N-苄基无赖氨酸视蛋白类似物
D-谷氨酸基抑制剂
抗糖尿病铬-2,4-噻唑烷二酮类
具有脑渗透性的GSK-3β抑制剂
作为 15-PGDH 抑制剂的噻唑烷二酮衍生物
放射增敏剂
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Effect of treatment with compressed CO2 and propane on D-hydantoinase activity
Andrade JM, et al.
Journal of Supercritical Fluids, 46(2), 342-350 (2008)
Y Thirupathi Reddy et al.
Bioorganic & medicinal chemistry letters, 20(2), 600-602 (2009-12-17)
A series of (Z)-5-((N-benzyl-1H-indol-3-yl)methylene)imidazolidine-2,4-dione (9a-9m) and 5-((N-benzyl-1H-indol-3-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-trione (10a-10i) derivatives that incorporate a variety of aromatic substituents in both the indole and N-benzyl moieties have been synthesized. These analogs were evaluated for their radiosensitization activity against the HT-29 cell line. Three
June Izquierdo et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 25(53), 12431-12438 (2019-07-19)
A bifunctional amine/squaramide catalyst promoted direct aldol addition of an hydantoin surrogate to pyridine 2-carbaldehyde N-oxides to afford adducts bearing two vicinal tertiary/quaternary carbons in high diastereo- and enantioselectivity (d.r. up to >20:1; ee up to 98 %) is reported. Acid
Narsimha Reddy Penthala et al.
Bioorganic & medicinal chemistry letters, 21(5), 1411-1413 (2011-02-08)
A series of novel substituted (Z)-5-((1-benzyl-1H-indol-3-yl)methylene)imidazolidin-2,4-diones (3a-f) and (Z)-5-((1-benzyl-1H-indol-3-yl)methylene)-2-iminothiazolidin-4-ones (3g-o) have been synthesized utilizing microwave irradiation. These analogs were evaluated for in vitro cytotoxicity against a panel of 60 human tumor cell lines. Compound 3i exhibits potent growth inhibition against
Ying Wu et al.
Bioorganic & medicinal chemistry, 18(4), 1428-1433 (2010-02-04)
Prostaglandins have a short life in vivo because they are metabolized rapidly by oxidation to 15-ketoprostaglandins catalyzed by a cytosolic enzyme known as NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH). Previously, CT-8, a thiazolidinedione analogue, was found to be a potent inhibitor of
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持