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196339

2-氧代-1-吡咯烷乙酸甲酯

Name: 2-氧代-1-吡咯烷乙酸甲酯
Brand: ALDRICH

96%

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关于此项目

经验公式（希尔记法）:

C₇H₁₁NO₃

化学文摘社编号:

59776-88-4

分子量:

157.17

UNSPSC Code:

12352100

PubChem Substance ID:

24851753

EC Number:

261-926-0

MDL number:

MFCD00003198

Assay:

96%

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属性

assay

96%

refractive index

n20/D 1.472 (lit.)

density

1.131 g/mL at 25 °C (lit.)

SMILES string

COC(=O)CN1CCCC1=O

InChI

1S/C7H11NO3/c1-11-7(10)5-8-4-2-3-6(8)9/h2-5H2,1H3

InChI key

HPDZYDTXCOFUOY-UHFFFAOYSA-N

说明

Application

Methyl 2-oxo-1-pyrrolidineacetate may be used in the synthesis of N-[(disubstituted-amino)alkyl]-2-oxo-1-pyrrolidineacetamide derivatives.

pictograms

GHS05,GHS07

signalword

Danger

hcodes

H302,H315,H318,H335

pcodes

P261 - P280 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam.

D E Butler et al.

Journal of medicinal chemistry, 27(5), 684-691 (1984-05-01)

A series of N-[(dialkylamino)alkyl]-2-oxo-1- pyrrolidineacetamides was synthesized. The title compounds reversed electroconvulsive shock (ECS) induced amnesia in mice when administered subsequent to the ECS treatment and were inactive in a general observational test for central nervous system (CNS) activity. Active