Enhance mAb Downstream Purification Efficiency
Improve productivity and remove bottlenecks with intensified multi column capture chromatography
Increase Productivity With Multi Column Capture Chromatography
The Mobius® Multi Column Capture system is a fully automated, single-use chromatography system designed for intensified Protein A capture using continuous capture chromatography. This three-column system empowers you with complete control of the capture step of your perfusion or fed-batch processes, and can be used for bioreactor volumes ranging from 50 L to 2000 L.
Intuitive software enables you to:
- Manage process parameters in real time: Adjust the column load and surge feed tank load, as well as monitor resin performance, to achieve more consistent operational efficiency.
- Configure and export data graphs to effectively track and analyze your operational performance.
- Minimize time and resources by performing dilution directly within the process.
Easy scalability for intensified downstream processing operations
It’s easier than ever to scale up your chromatography process development studies to the Mobius® Multi Column Capture system. Using a standard laboratory process development tool such as an ÄKTA system, you can effortlessly generate breakthrough curves, identify target mass loading, calculate media utilization, and define load and non-load times to assure continuous operations. The optimized parameters can be entered into the system interface for large-scale purification runs.
Case studies with the Mobius® Multi Column Capture system and our high-performing Eshmuno® A resin demonstrate you can confidently achieve seamless scale-up and simplify the implementation of more efficient, intensified capture operations.
Discover more on how to intensify your downstream process to maximize flexibility and increase productivity.
Related Resources
- Article: What is Multi Column Chromatography?
Multi column chromatography has the benefit of using less resin, increasing productivity, and enabling continuous processing. Learn more in this technical article.
- Article: How to Optimize Downstream Process Development for Scale Up to a Multicolumn Capture Chromatography System
Move towards Biopharma 4.0 and realize the benefits of multi column capture chromatography for intensified downstream process development.
Implement continuous capture chromatography to unlock operational flexibility
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