Recombinant Mouse IgG Antibody

Recombinant Mouse IgG Antibody

Finding the right blocker against a disruptive protein present in immunoassay test samples can be difficult given the constraints on consistency, reliability, and availability. For this reason, we have developed a novel, sustainable replacement for mouse IgG purified from animal serum. The new recombinant mouse IgG antibody provides immunoassay manufacturers with a tightly controlled, non-animal derived blocking solution to efficiently reduce nonspecific antibody interference while improving lot reproducibility and test accuracy.

Recombinant Mouse IgG Antibody Formulations

We offer two animal-free mouse IgG blocker antibody formulations: Recombinant Mouse IgG B1 and Recombinant Mouse IgG B2, both supported by a secure supply chain. These new blends were developed from unique clones produced in stable cell lines expressed in CHO cells.

• Recombinant Mouse IgG B1 is formulated as a direct alternative to serum-derived mouse IgG and employs a passive blocking approach to eliminate interfering antibodies from immunoassay systems using capture and detection antibodies.
• Recombinant Mouse IgG B2 is an enhanced formulation of B1, designed to deliver a targeted blocking strategy against anti-mouse antibodies in immunoassay sample serums.

An internal study was conducted to compare these recombinant mouse IgG antibodies against the serum-derived mouse IgG blockers that are currently available in the market. The results showcased that in an ELISA test, at a concentration of 1 mg/mL, the blends provided equivalent to better blocking efficiency. Read Now.