Improved Endotoxin Removal Using Eco-friendly Detergents for Intensified Plasmid DNA Capture
WEBINAR
Growing demand for high-quality plasmid DNA has increased the need for high productivity flexible manufacturing. Membrane chromatography provides an effective solution to alleviate the downstream bottleneck in plasmid purification.
This webinar will explore strategies for implementing an efficient and intensified plasmid removal process using anion exchange membrane chromatography. A comprehensive study evaluating the use of environmentally friendly detergents for enhanced endotoxin removal will be presented and the challenges faced by process developers will be addressed.
In this webinar, you will learn:
- Strategies to establish an efficient, intensified plasmid capture using convective anion exchange (AEX) chromatography.
- How this content is suitable for process development scientists and manufacturers
Speakers
André Kiesewetter
Merck
Senior Applications Engineer
André Kiesewetter is a senior applications engineer with more than twenty years of experience in Merck's downstream applications chromatography R&D team. In this role, he helps biopharmaceutical companies optimize, implement, and scale downstream technologies with a focus on developing best practices for the chromatographic purification of biomolecules. He has extensive expertise in bioprocessing operations and bioseparation technologies. André graduated from the University of Applied Sciences in Jena, Germany, with a degree in biotechnology engineering.
Oliver Prince
Merck
Senior Expert pDNA/mRNA/ GLP-1
Oliver Prince, Ph.D., is the Senior Modality Expert for pDNA, mRNA and GLP-1 for manufacturing and process understanding in the Americas. His current function is to connect customers and stakeholders to people, ideas and/or solutions to enable innovation and address unmet needs. His continued success in this space is facilitated by previous experience in science, marketing, strategy and serving patients.
Pharma and biopharma manufacturing
- Pharma and biopharma manufacturing
Duration:1h
Language:English
Session 1:presented September 9, 2025