CN
TP53
tumor protein p53
Synonyms:
BCC7, LFS1, P53, TRP53
Species:
Human TP53 (7157), Rat Tp53 (24842), Domestic Rabbit TP53 (100009292), domestic guinea pig Tp53 (100379269), sheep TP53 (443421), cow TP53 (281542), Zebrafish tp53 (30590), naked mole-rat Tp53 (101701769), dog TP53 (403869), chicken TP53 (396200) ...More
UniProtKB ID:
Gene ID:
- Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
- Rat(24842) tumor protein p53
- Domestic Rabbit(100009292) tumor protein p53
- domestic guinea pig(100379269) tumor protein p53
- sheep(443421) tumor protein p53
- cow(281542) tumor protein p53
- Zebrafish(30590) tumor protein p53
- naked mole-rat(101701769) tumor protein p53
- dog(403869) tumor protein p53
- chicken(396200) tumor protein p53
- Horse(100062044) tumor protein p53
- domestic cat(493847) tumor protein p53
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-p53 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-p53, antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-p53 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-p53 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-p53 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Cell Lines
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
p53 (1-363) C-terminal deletion human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human
p53 (1-342) C-terminal deletion human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
p53 (1-81), wild type, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
esiRNA
Product Number
Description
Species