Merck
CN

AFP

alpha-fetoprotein

Synonyms:
FETA, HPAFP
Species:
UniProtKB ID:
Gene ID:
  • Human(174) Summary: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
  • Mouse(11576) alpha fetoprotein
  • Rat(24177) alpha-fetoprotein
  • Horse(100034185) alpha-fetoprotein
  • dog(403551) alpha-fetoprotein
  • chicken(422652) alpha-fetoprotein
  • Domestic Rabbit(100345865) alpha-fetoprotein
  • cow(506011) alpha-fetoprotein
  • naked mole-rat(101725205) alpha-fetoprotein
  • domestic guinea pig(100728693) alpha-fetoprotein

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ELISA

Product Number
Description
Species
Human AFP / Alpha-fetoprotein ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
17α-Ethynylestradiol, ≥98%,
Species
human, rat
β-Estradiol, BioReagent, powder, suitable for cell culture,
Species
human, mouse, rat
β-Estradiol, ≥98%,
Species
human, mouse, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-AFP antibody produced in mouse, clone 1G7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunoprecipitation (IP)

western blot
Anti-Alpha-Fetoprotein antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP154, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-AFP antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-alphaFetoprotein antibody produced in mouse, clone AFP-11,
Species Reactivity
Application
immunohistochemistry
Monoclonal Anti-AFP antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9766, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human AFP,
Species
human