CN
APOB
apolipoprotein B
Synonyms:
FLDB, LDLCQ4
Species:
Human APOB (338), Mouse Apob (238055), Rat Apob (54225), domestic guinea pig Apob (100725937), Domestic Rabbit APOB (100009101), Horse APOB (100071824), cow APOB (494004), sheep APOB (101107590), chicken APOB (396535), domestic cat APOB (101098863) ...More
UniProtKB ID:
Gene ID:
- Human(338) Summary: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
- Mouse(238055) apolipoprotein B
- Rat(54225) apolipoprotein B
- domestic guinea pig(100725937) apolipoprotein B
- Domestic Rabbit(100009101) apolipoprotein B (including Ag(x) antigen)
- Horse(100071824) apolipoprotein B (including Ag(x) antigen)
- cow(494004) apolipoprotein B
- sheep(101107590) apolipoprotein B (including Ag(x) antigen)
- chicken(396535) apolipoprotein B (including Ag(x) antigen)
- domestic cat(101098863) apolipoprotein B (including Ag(x) antigen)
- dog(475680) apolipoprotein B (including Ag(x) antigen)
- naked mole-rat(101703081) apolipoprotein B
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-APOB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-APOB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-APOB antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-APOB antibody produced in mouse, clone 6G6, ascites fluid,
Species Reactivity
human
Application
ELISA
flow cytometry
immunofluorescence
western blot
flow cytometry
immunofluorescence
western blot
Anti-ApoB Antibody, clone 2T5X0, Rabbit Monoclonal, ,
Species Reactivity
mouse, rat
Application
western blot
Proteins
Product Number
Description
Species