CN
APOE
apolipoprotein E
Synonyms:
AD2, LDLCQ5, LPG
Species:
Human APOE (348), Mouse Apoe (11816), Rat Apoe (25728), naked mole-rat Apoe (101717206), domestic guinea pig Apoe (100731633), cow APOE (281004), Domestic Rabbit APOE (100009337), dog APOE (476438), domestic cat APOE (101086769)
UniProtKB ID:
Gene ID:
- Human(348) Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]
- Mouse(11816) apolipoprotein E
- Rat(25728) apolipoprotein E
- naked mole-rat(101717206) apolipoprotein E
- domestic guinea pig(100731633) apolipoprotein E
- cow(281004) apolipoprotein E
- Domestic Rabbit(100009337) apolipoprotein E
- dog(476438) apolipoprotein E
- domestic cat(101086769) apolipoprotein E
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-APOE antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APOE (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat, zebrafish
Application
immunohistochemistry
western blot
western blot
Anti-ApoE4 Fragment nApoECF Antibody (Asp172), from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Apolipoprotein E Mouse mAb (E6D7), liquid, clone E6D7, Calbiochem®,
Species Reactivity
human
Application
Monoclonal Anti-APOE antibody produced in mouse, clone 1H4, ascites fluid,
Species Reactivity
human
Application
ELISA
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
Apolipoprotein E4 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE and HPLC), lyophilized powder,
Species
human
esiRNA
Product Number
Description
Species