BAI1
brain-specific angiogenesis inhibitor 1
Synonyms:
GDAIF
Species:
Human BAI1 (575), Mouse Bai1 (107831), Rat Bai1 (362931), chicken BAI1 (100859755), domestic cat BAI1 (101086453), cow BAI1 (524070), domestic guinea pig Bai1 (100724586), naked mole-rat Bai1 (101715646), sheep BAI1 (101117595)
UniProtKB ID:
Gene ID:
- Human(575) Summary: Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008]
- Mouse(107831) brain-specific angiogenesis inhibitor 1
- Rat(362931) brain-specific angiogenesis inhibitor 1
- chicken(100859755) brain-specific angiogenesis inhibitor 1
- domestic cat(101086453) brain-specific angiogenesis inhibitor 1
- cow(524070) brain-specific angiogenesis inhibitor 1
- domestic guinea pig(100724586) brain-specific angiogenesis inhibitor 1
- naked mole-rat(101715646) brain-specific angiogenesis inhibitor 1
- sheep(101117595) brain-specific angiogenesis inhibitor 1
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-BAI1 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-BAI1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot