EDDM3B
epididymal protein 3B
Synonyms:
EP3B, FAM12B, HE3-BETA, HE3B
Species:
Human EDDM3B (64184), Mouse Eddm3b (219026), Rat Eddm3b (290032), domestic guinea pig Eddm3b (100721442), domestic cat EDDM3B (101091947), sheep EDDM3B (101113073)
UniProtKB ID:
Gene ID:
- Human(64184) Summary: Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq, Jul 2008]
- Mouse(219026) epididymal protein 3B
- Rat(290032) epididymal protein 3B
- domestic guinea pig(100721442) epididymal protein 3B
- domestic cat(101091947) epididymal protein 3B
- sheep(101113073) epididymal protein 3B
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