CN
EGFR
epidermal growth factor receptor
Synonyms:
ERBB, ERBB1, HER1, PIG61, mENA
Species:
Human EGFR (1956), Mouse Egfr (13649), Rat Egfr (24329), sheep EGFR (780479), domestic guinea pig Egfr (100725363), dog EGFR (404306), fruit fly Egfr (37455), Horse EGFR (100067755), cow EGFR (407217), naked mole-rat Egfr (101723771) ...More
UniProtKB ID:
Gene ID:
- Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(13649) epidermal growth factor receptor
- Rat(24329) epidermal growth factor receptor
- sheep(780479) epidermal growth factor receptor
- domestic guinea pig(100725363) epidermal growth factor receptor
- dog(404306) epidermal growth factor receptor
- fruit fly(37455) Epidermal growth factor receptor
- Horse(100067755) epidermal growth factor receptor
- cow(407217) epidermal growth factor receptor
- naked mole-rat(101723771) epidermal growth factor receptor
- domestic cat(100510799) epidermal growth factor receptor
- chicken(396494) epidermal growth factor receptor
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ELISA
Product Number
Description
Species
Phospho-EGFR (pTyr1045) ELISA Kit, for detection of human phospho-egfr (pTyr1045) in cell and tissue lysates,
Species
human
Phospho-EGFR (pTyr1068) ELISA Kit, for detection of human phospho-egfr (pTyr1068) in cell and tissue lysates,
Species
human
Cell-Based phospho-EGFR ELISA Sampler Kit, for detecting phospho-egfr(pTyr845), phospho-egfr(pTyr992), phospho-egfr(pTyr1068) and phospho-egfr in cultured cell lines,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Phospho-EGFR-Y1148 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
Anti-Phospho-EGFR-Y1068 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Phospho-EGFR-Y1045 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
Anti-Phospho-EGFR (Tyr1068) Antibody, clone 3F4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-EGFR Antibody, clone 7F12.1, clone 7F12.1, from mouse,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Gefitinib for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Proteins
Product Number
Description
Species
EGF-receptor human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human