G6PC2
glucose-6-phosphatase, catalytic, 2
Synonyms:
IGRP
Species:
Human G6PC2 (57818), Mouse G6pc2 (14378), Rat G6pc2 (170505), chicken G6PC2 (424171), cow G6PC2 (505012), sheep G6PC2 (101121493), dog G6PC2 (488389), Horse G6PC2 (100062750), domestic cat G6PC2 (101085486), naked mole-rat G6pc2 (101715644)
UniProtKB ID:
Gene ID:
- Human(57818) Summary: This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(14378) glucose-6-phosphatase, catalytic, 2
- Rat(170505) glucose-6-phosphatase, catalytic, 2
- chicken(424171) glucose-6-phosphatase, catalytic, 2
- cow(505012) glucose-6-phosphatase, catalytic, 2
- sheep(101121493) glucose-6-phosphatase, catalytic, 2
- dog(488389) glucose-6-phosphatase, catalytic, 2
- Horse(100062750) glucose-6-phosphatase, catalytic, 2
- domestic cat(101085486) glucose-6-phosphatase, catalytic, 2
- naked mole-rat(101715644) glucose-6-phosphatase, catalytic, 2
- domestic guinea pig(100736161) glucose-6-phosphatase, catalytic, 2
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