GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
Synonyms:
Species:
Human GNB3 (2784), Mouse Gnb3 (14695), Rat Gnb3 (60449), naked mole-rat Gnb3 (101718903), domestic guinea pig Gnb3 (100725705), cow GNB3 (513340), sheep GNB3 (101110493), chicken GNB3 (427945), dog GNB3 (403511), domestic cat GNB3 (101084799)
UniProtKB ID:
Gene ID:
- Human(2784) Summary: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described. [provided by RefSeq, Jul 2008]
- Mouse(14695) guanine nucleotide binding protein (G protein), beta 3
- Rat(60449) guanine nucleotide binding protein (G protein), beta polypeptide 3
- naked mole-rat(101718903) guanine nucleotide binding protein (G protein), beta polypeptide 3
- domestic guinea pig(100725705) guanine nucleotide binding protein (G protein), beta polypeptide 3
- cow(513340) guanine nucleotide binding protein (G protein), beta polypeptide 3
- sheep(101110493) guanine nucleotide binding protein (G protein), beta polypeptide 3
- chicken(427945) guanine nucleotide binding protein (G protein), beta polypeptide 3
- dog(403511) guanine nucleotide binding protein (G protein), beta polypeptide 3
- domestic cat(101084799) guanine nucleotide binding protein (G protein), beta polypeptide 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GNB3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species