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CN

GREM2

gremlin 2, DAN family BMP antagonist

Synonyms:
CKTSF1B2, DAND3, PRDC
Species:
UniProtKB ID:
Gene ID:
  • Human(64388) Summary: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008]
  • Mouse(23893) gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
  • Rat(289264) gremlin 2
  • chicken(421507) gremlin 2
  • Zebrafish(550399) gremlin 2, cysteine knot superfamily
  • domestic guinea pig(100731124) gremlin 2, DAN family BMP antagonist
  • dog(490367) gremlin 2
  • domestic cat(101096531) gremlin 2

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Mouse Grem2 / Gremlin-2 ELISA Kit, ,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GREM2 antibody produced in mouse, clone 4D9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Grem2,
Species
mouse