CN
GRM3
glutamate receptor, metabotropic 3
Synonyms:
GLUR3, GPRC1C, MGLUR3, mGlu3
Species:
Human GRM3 (2913), Mouse Grm3 (108069), Rat Grm3 (24416), domestic guinea pig Grm3 (100731837), naked mole-rat Grm3 (101713039), Zebrafish grm3 (565256), sheep GRM3 (101113057), dog GRM3 (100683236), Horse GRM3 (100049918), domestic cat GRM3 (101095810) ...More
UniProtKB ID:
Gene ID:
- Human(2913) Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Jul 2008]
- Mouse(108069) glutamate receptor, metabotropic 3
- Rat(24416) glutamate receptor, metabotropic 3
- domestic guinea pig(100731837) glutamate receptor, metabotropic 3
- naked mole-rat(101713039) glutamate receptor, metabotropic 3
- Zebrafish(565256) glutamate receptor, metabotropic 3
- sheep(101113057) glutamate receptor, metabotropic 3
- dog(100683236) glutamate receptor, metabotropic 3
- Horse(100049918) glutamate receptor, metabotropic 3
- domestic cat(101095810) glutamate receptor, metabotropic 3
- cow(541056) glutamate receptor, metabotropic 3
- chicken(418644) glutamate receptor, metabotropic 3
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Small Molecule - Agonist
Product Number
Description
Species
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Species
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Species
rat, human
Small Molecule - Antagonist
Product Number
Description
Species
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Species
rat, human
Small Molecule - Mixed Agonist/Antagonist
Product Number
Description
Species
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Species
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Species
rat, human
esiRNA
Product Number
Description
Species