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HLA-DMB

major histocompatibility complex, class II, DM beta

Synonyms:
D6S221E, RING7
Species:
Human HLA-DMB (3109)
UniProtKB ID:
P28068, O77936, Q13012, Q29751, Q58ZE2, Q5SNZ8, Q5STC4, Q9XRX2
Gene ID:
  • Human(3109) Summary: HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]

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Antibodies

Product Number
Description
Species Reactivity
Application
WH0003109M1
Monoclonal Anti-HLA-DMB antibody produced in mouse, clone 6B3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
SAB1409192
Monoclonal Anti-HLA-DMB antibody produced in mouse, clone 7D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
SAB1409193
Monoclonal Anti-HLA-DMB antibody produced in mouse, clone 4D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
SAB1409194
Monoclonal Anti-HLA-DMB antibody produced in mouse, clone 6E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
HPA012298
Anti-HLA-DMB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
EHU221511
MISSION® esiRNA, targeting human HLA-DMB,
Species
human