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LILRA3

leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3

Synonyms:
CD85E, HM31, HM43, ILT-6, ILT6, LIR-4, LIR4, e3
Species:
UniProtKB ID:
Gene ID:
  • Human(11026) Summary: Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-LILRA3 antibody produced in mouse, clone 2E9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human LILRA3,
Species
human