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LTBP4

latent transforming growth factor beta binding protein 4

Synonyms:
ARCL1C, LTBP-4, LTBP4L, LTBP4S
Species:
UniProtKB ID:
Gene ID:
  • Human(8425) Summary: The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
  • Mouse(108075) latent transforming growth factor beta binding protein 4
  • Rat(292734) latent transforming growth factor beta binding protein 4
  • domestic cat(101088448) latent transforming growth factor beta binding protein 4
  • dog(444849) latent transforming growth factor beta binding protein 4
  • sheep(101120267) latent transforming growth factor beta binding protein 4
  • cow(100848191) latent transforming growth factor beta binding protein 4
  • naked mole-rat(101699243) latent transforming growth factor beta binding protein 4
  • domestic guinea pig(100724798) latent transforming growth factor beta binding protein 4

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LTBP4 Antibody, clone 2M8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-LTBP4, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human LTBP4,
Species
human
MISSION® esiRNA, targeting mouse Ltbp4,
Species
mouse