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MANEA

mannosidase, endo-alpha

Synonyms:
ENDO, hEndo
Species:
UniProtKB ID:
Gene ID:
  • Human(79694) Summary: N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]
  • Mouse(242362) mannosidase, endo-alpha
  • Rat(140808) mannosidase, endo-alpha
  • domestic guinea pig(100718937) mannosidase, endo-alpha
  • dog(481925) mannosidase, endo-alpha
  • chicken(421807) mannosidase, endo-alpha
  • Zebrafish(447827) mannosidase, endo-alpha
  • sheep(101106778) mannosidase, endo-alpha
  • cow(512853) mannosidase, endo-alpha
  • Horse(100065922) mannosidase, endo-alpha
  • domestic cat(101101567) mannosidase, endo-alpha
  • naked mole-rat(101724745) mannosidase, endo-alpha

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MANEA antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-MANEA antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, human, mouse, rat
Application
western blot
Anti-MANEA antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MANEA,
Species
human
MISSION® esiRNA, targeting mouse Manea,
Species
mouse