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NDUFS8

NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)

Synonyms:
CI-23k, CI23KD, TYKY
Species:
UniProtKB ID:
Gene ID:
  • Human(4728) Summary: This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq, Mar 2010]
  • Mouse(225887) NADH dehydrogenase (ubiquinone) Fe-S protein 8
  • Rat(293652) NADH dehydrogenase (ubiquinone) Fe-S protein 8
  • domestic cat(101094451) NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
  • domestic guinea pig(100727207) NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
  • chicken(769492) NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
  • dog(610413) NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
  • naked mole-rat(101721961) NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
  • cow(287027) NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
  • sheep(101112935) NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NDUFS8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-NDUFS8 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-NDUFS8 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-NDUFS8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1,1-Dimethylbiguanide hydrochloride, 97%,
Species
human
Metformin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Metformin hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NDUFS8,
Species
human
MISSION® esiRNA, targeting mouse Ndufs8,
Species
mouse