PCDHA3
protocadherin alpha 3
Synonyms:
PCDH-ALPHA3
Species:
Human PCDHA3 (56145), Mouse Pcdha3 (192163), Rat Pcdha3 (116780), Horse PCDHA3 (100629863), dog PCDHA3 (607185), chicken PCDHA3 (497213), Zebrafish pcdha3 (100535181), naked mole-rat Pcdha3 (101725180), domestic guinea pig Pcdha3 (100713314)
UniProtKB ID:
Gene ID:
- Human(56145) Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
- Mouse(192163) protocadherin alpha 3
- Rat(116780) protocadherin alpha 3
- Horse(100629863) protocadherin alpha 3
- dog(607185) protocadherin alpha 3
- chicken(497213) protocadherin alpha 3
- Zebrafish(100535181) protocadherin alpha 3
- naked mole-rat(101725180) protocadherin alpha 3
- domestic guinea pig(100713314) protocadherin alpha 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PCDHA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
esiRNA
Product Number
Description
Species