PDZD3
PDZ domain containing 3
Synonyms:
IKEPP, NHERF4, PDZK2
Species:
Human PDZD3 (79849), Mouse Pdzd3 (170761), Rat Pdzd3 (500986), chicken PDZD3 (769876), cow PDZD3 (539171), sheep PDZD3 (101108682), dog PDZD3 (610585), domestic cat PDZD3 (101084649), Domestic Rabbit PDZD3 (100342091), naked mole-rat Pdzd3 (101707271) ...More
UniProtKB ID:
Gene ID:
- Human(79849) Summary: Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]
- Mouse(170761) PDZ domain containing 3
- Rat(500986) PDZ domain containing 3
- chicken(769876) PDZ domain containing 3
- cow(539171) PDZ domain containing 3
- sheep(101108682) PDZ domain containing 3
- dog(610585) PDZ domain containing 3
- domestic cat(101084649) PDZ domain containing 3
- Domestic Rabbit(100342091) PDZ domain containing 3
- naked mole-rat(101707271) PDZ domain containing 3
- domestic guinea pig(100718781) PDZ domain containing 3
- Horse(100071387) PDZ domain containing 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PDZD3 antibody produced in mouse, clone 1F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-PDZD3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry