Merck
CN

PPAT

phosphoribosyl pyrophosphate amidotransferase

Synonyms:
ATASE, GPAT, PRAT
Species:
UniProtKB ID:
Gene ID:
  • Human(5471) Summary: The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq, Mar 2011]
  • Mouse(231327) phosphoribosyl pyrophosphate amidotransferase
  • Rat(117544) phosphoribosyl pyrophosphate amidotransferase
  • sheep(101109095) phosphoribosyl pyrophosphate amidotransferase
  • chicken(422743) phosphoribosyl pyrophosphate amidotransferase
  • Horse(100053805) phosphoribosyl pyrophosphate amidotransferase
  • domestic cat(101084957) phosphoribosyl pyrophosphate amidotransferase
  • cow(509652) phosphoribosyl pyrophosphate amidotransferase
  • domestic guinea pig(100730194) phosphoribosyl pyrophosphate amidotransferase
  • naked mole-rat(101720775) phosphoribosyl pyrophosphate amidotransferase
  • dog(611407) phosphoribosyl pyrophosphate amidotransferase
  • Zebrafish(572027) phosphoribosyl pyrophosphate amidotransferase
  • Domestic Rabbit(100348590) phosphoribosyl pyrophosphate amidotransferase

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PPAT antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-PPAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-PPAT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PPAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PPAT antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Azathioprine, ≥98%,
Species
human
6-Mercaptopurine monohydrate, 98%,
Species
human
Azathioprine, United States Pharmacopeia (USP) Reference Standard,
Species
human
Azathioprine, European Pharmacopoeia (EP) Reference Standard,
Species
human
Azathioprine, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PPAT,
Species
human
MISSION® esiRNA, targeting mouse Ppat,
Species
mouse