SCARB2
scavenger receptor class B, member 2
Synonyms:
AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII
Species:
Human SCARB2 (950), Mouse Scarb2 (12492), Rat Scarb2 (117106), dog SCARB2 (478435), Domestic Rabbit SCARB2 (100352345), sheep SCARB2 (101105502), cow SCARB2 (533177), naked mole-rat Scarb2 (101715798), domestic guinea pig Scarb2 (100716020), chicken SCARB2 (422638) ...More
UniProtKB ID:
Gene ID:
- Human(950) Summary: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
- Mouse(12492) scavenger receptor class B, member 2
- Rat(117106) scavenger receptor class B, member 2
- dog(478435) scavenger receptor class B, member 2
- Domestic Rabbit(100352345) scavenger receptor class B, member 2
- sheep(101105502) scavenger receptor class B, member 2
- cow(533177) scavenger receptor class B, member 2
- naked mole-rat(101715798) scavenger receptor class B, member 2
- domestic guinea pig(100716020) scavenger receptor class B, member 2
- chicken(422638) scavenger receptor class B, member 2
- Zebrafish(192340) scavenger receptor class B, member 2
- domestic cat(101098789) scavenger receptor class B, member 2
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SCARB2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-LIMP2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
KD-Validated Anti SCARB2 Antibody, clone 24GB1520, Rabbit Monoclonal, clone 24GB1520, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
western blot
western blot
Anti-SCARB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-SR-B2/LIMPII antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot