CN
SP1
Sp1 transcription factor
Synonyms:
Species:
Human SP1 (6667), Mouse Sp1 (20683), Rat Sp1 (24790), Zebrafish sp1 (324109), fruit fly Sp1 (31913), chicken SP1 (395303), dog SP1 (486507), domestic cat SP1 (101100227), cow SP1 (540741), Goat SP1 (100860911) ...More
UniProtKB ID:
Gene ID:
- Human(6667) Summary: The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Mouse(20683) trans-acting transcription factor 1
- Rat(24790) Sp1 transcription factor
- Zebrafish(324109) sp1 transcription factor
- fruit fly(31913) CG1343 gene product from transcript CG1343-RE
- chicken(395303) Sp1 transcription factor
- dog(486507) Sp1 transcription factor
- domestic cat(101100227) Sp1 transcription factor
- cow(540741) Sp1 transcription factor
- Goat(100860911) Sp1 transcription factor
- sheep(101104139) Sp1 transcription factor
- sheep(100303456) Sp1 transcription factor
- Domestic Rabbit(100351317) Sp1 transcription factor
- domestic guinea pig(100726500) Sp1 transcription factor
- naked mole-rat(101697506) Sp1 transcription factor
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SP1 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Sp1 Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
ChIP
electrophoretic mobility shift assay
immunofluorescence
immunoprecipitation (IP)
western blot
electrophoretic mobility shift assay
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-Sp1 Antibody, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-phospho-SP1 (pThr453) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Rabbit anti-Sp1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
ChIP
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Proteins
Product Number
Description
Species
Sp1 GC-box binding protein human, recombinant, expressed in insect cells, ≥75% (SDS-PAGE),
Species
human
Sp1 (GC-box binding protein), GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human