SPACA1
sperm acrosome associated 1
Synonyms:
SAMP32
Species:
Human SPACA1 (81833), Mouse Spaca1 (67652), Rat Spaca1 (500432), domestic cat SPACA1 (101091941), chicken SPACA1 (421820), sheep SPACA1 (101112231), naked mole-rat Spaca1 (101703197), dog SPACA1 (611635), domestic guinea pig Spaca1 (100728130), cow SPACA1 (614884)
UniProtKB ID:
Gene ID:
- Human(81833) Summary: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. [provided by RefSeq, Jul 2008]
- Mouse(67652) sperm acrosome associated 1
- Rat(500432) sperm acrosome associated 1
- domestic cat(101091941) sperm acrosome associated 1
- chicken(421820) sperm acrosome associated 1
- sheep(101112231) sperm acrosome associated 1
- naked mole-rat(101703197) sperm acrosome associated 1
- dog(611635) sperm acrosome associated 1
- domestic guinea pig(100728130) sperm acrosome associated 1
- cow(614884) sperm acrosome associated 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SPACA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-SPACA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry