SURF1
surfeit 1
Synonyms:
Species:
Human SURF1 (6834), Mouse Surf1 (20930), Rat Surf1 (64463), sheep SURF1 (101113488), cow SURF1 (100139115), chicken SURF1 (417157), Zebrafish surf1 (557970), domestic guinea pig Surf1 (100717386), fruit fly Surf1 (44498), naked mole-rat Surf1 (101710326) ...More
UniProtKB ID:
Gene ID:
- Human(6834) Summary: This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq, Jul 2008]
- Mouse(20930) surfeit gene 1
- Rat(64463) surfeit 1
- sheep(101113488) surfeit 1
- cow(100139115) surfeit 1
- chicken(417157) surfeit 1
- Zebrafish(557970) surfeit 1
- domestic guinea pig(100717386) surfeit 1
- fruit fly(44498) Surfeit 1
- naked mole-rat(101710326) surfeit 1
- Thale Cress(821310) Surfeit locus 1 cytochrome c oxidase biogenesis protein
- domestic cat(101085249) surfeit 1
- dog(480681) surfeit 1
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