Merck
CN

TNFRSF18

tumor necrosis factor receptor superfamily, member 18

Synonyms:
AITR, CD357, GITR, GITR-D
Species:
UniProtKB ID:
Gene ID:
  • Human(8784) Summary: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
  • Mouse(21936) tumor necrosis factor receptor superfamily, member 18
  • Rat(500598) tumor necrosis factor receptor superfamily, member 18
  • sheep(101108672) tumor necrosis factor receptor superfamily, member 18
  • domestic cat(101083251) tumor necrosis factor receptor superfamily, member 18
  • domestic guinea pig(100715459) tumor necrosis factor receptor superfamily, member 18
  • naked mole-rat(101715065) tumor necrosis factor receptor superfamily, member 18
  • cow(516256) tumor necrosis factor receptor superfamily, member 18
  • dog(606971) tumor necrosis factor receptor superfamily, member 18
  • Zebrafish(571217) tumor necrosis factor receptor superfamily, member 18
  • chicken(419424) tumor necrosis factor receptor superfamily, member 18

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ELISA

Product Number
Description
Species
Mouse Tnfrsf18 ELISA Kit, ,
Species
mouse
Human GITR / TNFRSF18 ELISA Kit, for cell and tissue lysates,
Species
human
Human GITR / TNFRSF18 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-hGITR Antibody, clone 108-17, clone 108-17, from mouse,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-TNFRSF18 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL7787, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
western blot
Anti-TNFRSF18 (soluble form) Antibody, clone T10P2H9*B9, clone T10P2H9*B9, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-TNFRSF18 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-TNFRSF18 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot

Proteins

Product Number
Description
Species
CD40, FC Fusion, recombinant, expressed in HEK 293 cells,
Species
human
GITR (CD357), FC Fusion, recombinant, expressed in HEK 293 cells,
Species
human
GITR (CD357), FC Fusion, Biotin Labeled, recombinant, expressed in HEK 293 cells,
Species
human