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Merck
CN

21192

Calcium ionophore I

Selectophore™, function tested, ≥99.0%

Synonym(s):

(−)-(R,R)-N,N′-Bis-[11-(ethoxycarbonyl)undecyl]-N,N′,4,5-tetramethyl-3,6-dioxaoctane-diamide, Diethyl N,N′-[(4R,5R)-4,5-dimethyl-1,8-dioxo-3,6-dioxaoctamethylene]bis(12-methylaminododecanoate), ETH 1001

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About This Item

Empirical Formula (Hill Notation):
C38H72N2O8
CAS Number:
58801-34-6
Molecular Weight:
684.99
UNSPSC Code:
26111700
NACRES:
NB.61
PubChem Substance ID:
329752115
EC Number:
261-449-8
Beilstein/REAXYS Number:
2343275
MDL number:
MFCD00042943
Assay:
≥99.0% (HPLC)
≥99.0%
Quality level:
200

Key Documents

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Product Name

Calcium ionophore I, Selectophore™, function tested, ≥99.0%

InChI key

CJAONIOAQZUHPN-KKLWWLSJSA-N

InChI

1S/C38H72N2O8/c1-7-45-37(43)27-23-19-15-11-9-13-17-21-25-29-39(5)35(41)31-47-33(3)34(4)48-32-36(42)40(6)30-26-22-18-14-10-12-16-20-24-28-38(44)46-8-2/h33-34H,7-32H2,1-6H3/t33-,34-/m1/s1

SMILES string

CCOC(=O)CCCCCCCCCCCN(C)C(=O)CO[C@H](C)[C@@H](C)OCC(=O)N(C)CCCCCCCCCCCC(=O)OCC

description

for ion-selective electrodes

product line

Selectophore™

assay

≥99.0% (HPLC)
≥99.0%

quality

function tested

Quality Level

200

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Application

Selected application examples
Calcium ionophore I (ETH 1001) was used in an experimental study, conducted to determine the intracellular and extracellular changes of calcium ions in hypoxia and ischemia in rat brain.

General description

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Other Notes

Used as ionophore in membrane electrodes for the determination of Ca2+-activities; Useful for transport studies in biological membranes.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN2793
BCCN2792
BCCM6200
BCCM8844
BCCM8843

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I A Silver et al.
The Journal of general physiology, 95(5), 837-866 (1990-05-01)
Changes in intra- and extracellular free calcium concentration were evaluated with ion-selective microelectrodes during periods of anoxia and ischemia in three different regions of intact rat brain. Recordings stable for at least 2 min and in most cases for 4-6
W. Simon et al.
Annals of the New York Academy of Sciences, 307, 52-52 (1978)
P Caroni et al.
Biochimica et biophysica acta, 470(3), 437-445 (1977-11-01)
The effect of a synthetic neutral ligand on the Ca2+ permeability of several biological membranes has been investigated. The ligand had been previously shown to possess Ca2+ -ionophoric activities in artificial phospholipid membranes. The neutral ionophore is able to transport
Anna Kisiel et al.
Talanta, 220, 121358-121358 (2020-09-16)
An alternative optical signal transduction mechanism for ion-selective optodes is proposed. The nanostructural sensors benefit from ion-selective reversing aggregation caused quenching yielding turn-on, bright and highly stable optical signals. Selective incorporation of analyte results in transformation of the polymer dye
Zachary J Sandler et al.
Antimicrobial agents and chemotherapy, 64(6) (2020-04-15)
Bunyaviruses are significant human pathogens, causing diseases ranging from hemorrhagic fevers to encephalitis. Among these viruses, La Crosse virus (LACV), a member of the California serogroup, circulates in the eastern and midwestern United States. While LACV infection is often asymptomatic
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Selectophore Ionophores

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