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G5516

Glycerol

Name: Glycerol
Brand: SIGMA

Molecular Biology, ≥99.0%

Synonym(s):

1,2,3-Propanetriol, Glycerin

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About This Item

Linear Formula:

HOCH₂CH(OH)CH₂OH

CAS Number:

56-81-5

Molecular Weight:

92.09

UNSPSC Code:

50161901

NACRES:

NA.31

PubChem Substance ID:

24895216

EC Number:

200-289-5

Beilstein/REAXYS Number:

635685

MDL number:

MFCD00004722

Assay:

≥99.0%

Grade:

Molecular Biology, reagent grade

Technique(s):

MALDI-MS: suitable, cryopreservation: suitable

Bp:

182 °C/20 mmHg (lit.)

Vapor pressure:

<1 mmHg ( 20 °C)

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Quality Level

200

grade

Molecular Biology, reagent grade

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

assay

≥99.0%

form

viscous liquid

autoignition temp.

698 °F

expl. lim.

≥2.7-19.0 %

greener alternative product characteristics

Safer Solvents and Auxiliaries
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

MALDI-MS: suitable, cryopreservation: suitable

impurities

<5 ppm Iron, <5 ppm heavy metal, <5 ppm magnesium

refractive index

n20/D 1.474 (lit.)

pH

5.5-8

bp

182 °C/20 mmHg (lit.)

mp

20 °C (lit.)

solubility

water: 1 mL/mL, clear, colorless

density

1.25 g/mL (lit.)

cation traces

Fe: ≤5 ppm, Mg: ≤5 ppm, heavy metals (as Pb): <5 ppm

application(s)

life science and biopharma
microbiology
sample preservation

foreign activity

DNase, RNase, NICKase, and protease, none detected

greener alternative category

Aligned

SMILES string

OCC(O)CO

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

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Biochemicals

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General description

Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. Glycerol, with its high boiling point, low flammability, and polarity, is a standout choice. As a non-toxic and biodegradable compound, it aligns perfectly with the principles of ′Safer Solvents and Auxiliaries′ and ′Design for Degradation′. Click here for more information.

Application

Glycerol has been used as:

a component of mounting medium for immunofluorescence
a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium.
a fuel during the designing of enzymatic biofuel cells.
a liquid composite matrix with 4-HCCA and 3-aminoquinoline for analysis of neutral and acidic glycans.
a matrix for fast atom bombardment MS.

Glycerol may be employed as a liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis.

Biochem/physiol Actions

Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release.

Features and Benefits

This product has been analyzed for the presence of nucleases and proteases.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

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The product is intended for laboratory use only, and it is not suitable for drug, household, or other purposes.

Storage Class

10 - Combustible liquids

flash_point_f

390.2 °F - Pensky-Martens closed cup

flash_point_c

199 °C - Pensky-Martens closed cup

ppe

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Comparison of the sensitivities of various derivatives of oligosaccharides in LC/MS with fast atom bombardment and electrospray ionization interfaces

Suzuki, Shigeo, Kazuaki Kakehi, and Susumu Honda

Analytical Chemistry, 68 (13) , 2073-2083 (1996)

Ionic-liquid matrices for quantitative analysis by MALDI-TOF mass spectrometry

Li, Ying L., and Michael L. Gross

Journal of the American Society For Mass Spectrometry, 15 (12), 1833-1837 (2004)

Development of glycerol/O 2 biofuel cell

Arechederra, Robert L., Becky L. Treu, and Shelley D. Minteer

Journal of Power Sources, 173 (1), 156-161 (2007)

Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium

Collins, L., and Scott G. Franzblau

Antimicrobial Agents and Chemotherapy, 41 (5), 1004-1009 (1997)

Gellan gum incorporating titanium dioxide nanoparticles biofilm as wound dressing: Physicochemical, mechanical, antibacterial properties and wound healing studies.

Nur Arifah Ismail et al.

Materials science & engineering. C, Materials for biological applications, 103, 109770-109770 (2019-07-28)

In this work, the potential of titanium dioxide nanoparticles incorporated gellan gum (GG + TiO2-NPs) biofilm as wound dressing material was investigated. The GG + TiO2-NPs biofilm was prepared via evaporative casting technique and was characterized using FTIR, XRD, and SEM to study their

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使用磷酸钙将DNA转入真核细胞是一种常见的转染方法。该转染实验方案可经优化用于各种细胞类型。

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Global Trade Item Number

SKU	GTIN
G5516-100ML	04061838255679
G5516-1L	04061838255686
G5516-1VL	04061833296394
G5516-4L	04061838255693
G5516-500ML	04061838255709

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