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Merck
CN

127256

N,N-Diethyltrimethylsilylamine

97%

Synonym(s):

(Diethylamino)trimethylsilane, N-(Trimethylsilyl)diethylamine, TMSDEA

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About This Item

Linear Formula:
(C2H5)2NSi(CH3)3
CAS Number:
Molecular Weight:
145.32
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
213-637-6
Beilstein/REAXYS Number:
635718
MDL number:
Assay:
97%
Form:
liquid
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InChI key

JOOMLFKONHCLCJ-UHFFFAOYSA-N

InChI

1S/C7H19NSi/c1-6-8(7-2)9(3,4)5/h6-7H2,1-5H3

SMILES string

CCN(CC)[Si](C)(C)C

vapor density

>1 (vs air)

assay

97%

form

liquid

refractive index

n20/D 1.411 (lit.)

bp

125-126 °C (lit.)

density

0.767 g/mL at 25 °C (lit.)

functional group

amine

Quality Level

General description

N,N-Diethyltrimethylsilylamine is a silylating agent used to derivatize polar organic compounds.

pictograms

FlameCorrosion

signalword

Danger

hcodes

Hazard Classifications

Flam. Liq. 2 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

48.2 °F - closed cup

flash_point_c

9 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

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Sujatha Chilakala et al.
Analytical biochemistry, 566, 62-66 (2018-11-13)
A method is proposed in this paper for the determination of oxygen-18 labeled phosphate so that positional isotope experiments using sensitive and rapid liquid chromatography-QTOF-mass spectrometry (LC-QTOF-MS) experiments can be carried out. The positional isotope exchange technique is a useful
Said Kinani et al.
Journal of chromatography. A, 1190(1-2), 307-315 (2008-04-09)
This study compares different silylation procedures of zearalenone and its metabolites: alpha-zearalenol, beta-zearalenol, zearalanone, alpha-zearalanol and beta-zearalanol for gas chromatography-mass spectrometry (GC-MS) analysis. Four silylating agents among the most frequently used to derivatize polar organic compounds were tested: N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA)

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