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Merck
CN

146188

2-Hydroxy-5-methoxybenzoic acid

98%

Synonym(s):

5-Methoxysalicylic acid

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About This Item

Linear Formula:
CH3OC6H3(OH)CO2H
CAS Number:
Molecular Weight:
168.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-037-8
Beilstein/REAXYS Number:
2209647
MDL number:
Assay:
98%
Form:
powder
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assay

98%

form

powder

mp

141-143 °C (lit.)

functional group

carboxylic acid

SMILES string

COc1ccc(O)c(c1)C(O)=O

InChI

1S/C8H8O4/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4,9H,1H3,(H,10,11)

InChI key

IZZIWIAOVZOBLF-UHFFFAOYSA-N

General description

2-Hydroxy-5-methoxybenzoic acid is matrix additive which enhances the electrical conductivity of the matrix crystal during matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).

Application

2-Hydroxy-5-methoxybenzoic acid was used to evaluate MALDI matrix/solvent combinations for intact spore mass spectrometry of Fusarium species.


Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Osmond D Rebello et al.
Frontiers in chemistry, 8, 138-138 (2020-03-19)
Changes in the abundance of antennary fucosylated glycans in human total plasma N-glycome (TPNG) have been associated with several diseases ranging from diabetes to various forms of cancer. However, it is challenging to address this important part of the human
T Nishihata et al.
Diabetes, 30(12), 1065-1067 (1981-12-01)
Sodium 5-methoxysalicylate, previously shown to enhance the rectal absorption of several drugs, facilitates the absorption of insulin from the upper gastrointestinal tract, resulting in significantly elevated insulin levels and lowered glucose concentrations in the plasma of rats. Restricting the movement
Cole Emanuelson et al.
SLAS discovery : advancing life sciences R & D, 26(1), 58-66 (2020-09-30)
High-throughput matrix-assisted laser desorption/ionization mass spectrometry (HT-MALDI-MS) has garnered considerable attention within the drug discovery industry as an information-rich alternative to assays using light-based detection methods. To date, these efforts have been primarily focused on assays using protein or peptide



Global Trade Item Number

SKUGTIN
146188-50G04061831818680
146188-10G04061838736635