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Sigma-Aldrich

Diphenylcyclopropenone

98%

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Synonym(s):
DPC
Empirical Formula (Hill Notation):
C15H10O
CAS Number:
886-38-4
Molecular Weight:
206.24
Beilstein:
608049
EC Number:
212-948-4
MDL number:
MFCD00001311
PubChem Substance ID:
24850631
NACRES:
NA.22

Quality Level

100

Assay

98%

mp

118-122 °C (lit.)

SMILES string

O=C1C(c2ccccc2)=C1c3ccccc3

InChI

1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H

InChI key

HCIBTBXNLVOFER-UHFFFAOYSA-N

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General description

Diphenylcyclopropenone is a potent hapten. Its vibration frequency has been evaluated.

Application

Diphenylcyclopropenone was used in topical immunotherapy.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Precautionary Statements

P280 - P302 + P352

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T Kjeld et al.
Scandinavian journal of medicine & science in sports, 25(3), e253-e257 (2014-08-22)
Free diving is associated with extreme hypoxia. This study evaluated the combined effect of maximal static breath holding and underwater swimming on plasma biomarkers of tissue hypoxemia: erythropoietin, neuron-specific enolase and S100B, C-reactive protein, pro-atrial natriuretic peptide, and troponin T.
Yunseok Choi et al.
Annals of dermatology, 25(4), 434-439 (2013-12-29)
There exists a treatment challenge with periungual warts. Topical immunotherapy with diphenylcyclopropenone (DPCP) has recently been reported to be an effective treatment for recalcitrant warts, including periungual types. We aimed to evaluate the effectiveness and preference of topical immunotherapy with
Valerio Tabacchini et al.
Physics in medicine and biology, 60(14), 5513-5525 (2015-07-03)
Gamma-ray detectors based on bright monolithic scintillation crystals coupled to pixelated photodetectors are currently being considered for several applications in the medical imaging field. In a typical monolithic detector, both the light intensity and the time of arrival of the
M C Ohlmeier et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 26(4), 503-507 (2011-05-17)
Although diphenylcyclopropenone (DCP) is frequently used for the treatment of alopecia areata (AA), large studies with more than 100 patients are still scarce. To determine the efficacy of DCP immunotherapy in a large cohort of patients with AA who had
S von Moos et al.
Allergy, 67(5), 638-646 (2012-03-03)
Epicutaneous vaccination has gained increasing interest during the past decade as it offers a safe, needle-free, and patient-friendly alternative to invasive vaccine administrations. Recently, the safety and early efficacy of epicutaneous immunotherapy were also demonstrated in patients with hay fever
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