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Merck
CN

262528

N,N-Diisopropylmethylphosphonamidic chloride

95%, liquid

Synonym(s):

Chloro(diisopropylamino)methoxyphosphine, Methyl N,N-diisopropylchlorophosphoramidite, Methyl N,N-diisopropylphosphoramidochloridite

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About This Item

Linear Formula:
[(CH3)2CH]2NP(OCH3)Cl
CAS Number:
Molecular Weight:
197.64
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352001
MDL number:
Beilstein/REAXYS Number:
3600769
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Product Name

N,N-Diisopropylmethylphosphonamidic chloride, 95%

InChI

1S/C7H17ClNOP/c1-6(2)9(7(3)4)11(8)10-5/h6-7H,1-5H3

SMILES string

COP(Cl)N(C(C)C)C(C)C

InChI key

VOVWQRQDSCYAEA-UHFFFAOYSA-N

assay

95%

form

liquid

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling

refractive index

n20/D 1.468 (lit.)

bp

34-35 °C/0.8 mmHg (lit.)

density

1.018 g/mL at 25 °C (lit.)

Quality Level

Application

Reagent used for polymer-supported deoxyoligonucleotide and oligoribonucleotide syntheses.

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

161.6 °F - closed cup

flash_point_c

72 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Journal of the Chemical Society. Perkin Transactions 1, 747-747 (1993)
Aldrichimica Acta, 16, 47-47 (1983)
Tetrahedron Letters, 34, 2195-2195 (1993)

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