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Merck
CN

285749

DL-Ephedrine hydrochloride

99%

Synonym(s):

(±)-2-Ephedrinium hydrochloride, (±)-Ephedrine hydrochloride, DL-erythro-Ephedrine hydrochloride

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About This Item

Linear Formula:
C6H5CH(OH)CH(CH3)NHCH3 · HCl
CAS Number:
134-71-4
Molecular Weight:
201.69
EC Number:
205-153-9
MDL number:
MFCD00012626
UNSPSC Code:
12352100
PubChem Substance ID:
24857224
NACRES:
NA.22

Key Documents

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Quality Level

100

Assay

99%

form

solid

mp

188-190 °C

solubility

H2O: soluble 5%, clear, colorless

functional group

amine
hydroxyl
phenyl

SMILES string

Cl.CN[C@H](C)[C@@H](O)c1ccccc1

InChI

1S/C10H15NO.ClH/c1-8(11-2)10(12)9-6-4-3-5-7-9;/h3-8,10-12H,1-2H3;1H/t8-,10-;/m1./s1

InChI key

BALXUFOVQVENIU-GHXDPTCOSA-N

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General description

Ephedrine hydrochloride is an active α- and β-adrenergic agonist. It has also been reported to be effective in treating daytime urinary incontinence in children.

Application

Ephedrine hydrochloride was used in the control of the inflammatory response. It was also used to treat hypotension caused by either anesthesia or overdose of antihypertensive drugs.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H317,H412

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB3199
STBL1581
STBJ8811
STBJ5801
STBG2436V

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Yuejuan Zheng et al.
International immunopharmacology, 13(1), 46-53 (2012-03-27)
Sepsis and its derivative endotoxic shock are still serious conditions with high mortality in the intensive care unit. The mechanisms that ensure the balance of proinflammatory cytokines and anti-inflammatory cytokine production are of particular importance. As an active α- and
Neil Featherstone et al.
Journal of pediatric urology, 9(6 Pt A), 915-918 (2013-01-22)
To determine whether the adrenoceptor agonist, ephedrine hydrochloride, is an effective treatment for resistant non-neurogenic daytime urinary incontinence in children. From 2000 to 2010, eighteen children with resistant non-neurogenic daytime urinary incontinence were treated with oral ephedrine hydrochloride at our
Yuejuan Zheng et al.
Cellular & molecular immunology, 10(4), 330-337 (2013-04-23)
Approaches for controlling inflammatory responses and reducing the mortality rate of septic patients remain clinically ineffective; new drugs need to be identified that can induce anti-inflammatory responses. Ephedrine hydrochloride (EH) is a compound that is widely used in cardiovascular diseases
Noel Kong et al.
Journal of separation science, 37(21), 3015-3023 (2014-08-22)
A sensitive hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry method was developed and validated for the simultaneous detection and quantification of etilefrine and oxilofrine in equine blood plasma and urine. The method is highly sensitive and specific with

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