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Merck
CN

457647

Poly(D,L-lactide-co-caprolactone)

DL-lactide 86 mol %

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About This Item

UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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Product Name

Poly(D,L-lactide-co-caprolactone), DL-lactide 86 mol %

InChI

1S/C5H10O3.C3H6O3/c6-4-2-1-3-5(7)8;1-2(4)3(5)6/h6H,1-4H2,(H,7,8);2,4H,1H3,(H,5,6)

InChI key

LLHKFIFJPCHEOM-UHFFFAOYSA-N

SMILES string

CC(O)C(O)=O.OCCCCC(O)=O

form

solid

feed ratio

lactide:caprolactone 85:15

composition

DL-lactide, 86 mol %

inherent viscosity

0.7-0.9 dL/g, in chloroform(lit.)

transition temp

Tg 16 °C

storage temp.

2-8°C

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Application

Poly(DL-lactide-co-caprolactone) (PLA-PCL) is a biodegradable block copolymer that may be used as monofilament sutures and nanoparticle-based drug delivery systems.

Features and Benefits

Biocompatible, biodegradable polymer.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Polymeric scaffolds in tissue engineering application: a review.
Dhandayuthapani B, et al.
International Journal of Polymer Science (2011)
Novel docetaxel-loaded nanoparticles based on poly (lactide-co-caprolactone) and poly (lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies.
Sanna V, et al.
Nanoscale Research Letters, 6(1), 260-260 (2011)

Articles

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

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