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46920

Fmoc N-hydroxysuccinimide ester

Name: Fmoc <I>N</I>-hydroxysuccinimide ester
Brand: ALDRICH

≥98.0% (HPLC), for peptide synthesis

Synonym(s):

9-Fluorenylmethyl N-succinimidyl carbonate, N-(9-Fluorenylmethoxycarbonyloxy)succinimide, Fmoc-OSu

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About This Item

Empirical Formula (Hill Notation):

C₁₉H₁₅NO₅

CAS Number:

82911-69-1

Molecular Weight:

337.33

NACRES:

NA.22

PubChem Substance ID:

57650882

UNSPSC Code:

12352108

EC Number:

433-520-5

MDL number:

MFCD00010733

Beilstein/REAXYS Number:

3569540

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Properties

Product Name

Fmoc N-hydroxysuccinimide ester, ≥98.0% (HPLC)

Quality Level

200

assay

≥98.0% (HPLC)

form

powder

mp

150-153 °C (lit.)

application(s)

peptide synthesis

functional group

Fmoc, imide

storage temp.

2-8°C

SMILES string

O=C(OCC1c2ccccc2-c3ccccc13)ON4C(=O)CCC4=O

InChI

1S/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2

InChI key

WMSUFWLPZLCIHP-UHFFFAOYSA-N

Description

Application

Most efficient reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxy-amino acids in high yield. Dipeptide formation is lower than with the chloroformate, Fmoc-Cl. It has been employed in the synthesis of glycopeptides.