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Merck
CN

469475

(R)-(+)-3-(Benzyloxycarbonyl)-4-oxazolidinecarboxylic acid

98%

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About This Item

Empirical Formula (Hill Notation):
C12H13NO5
CAS Number:
Molecular Weight:
251.24
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
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Product Name

(R)-(+)-3-(Benzyloxycarbonyl)-4-oxazolidinecarboxylic acid, 98%

assay

98%

InChI

1S/C12H13NO5/c14-11(15)10-7-17-8-13(10)12(16)18-6-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,14,15)/t10-/m1/s1

SMILES string

OC(=O)[C@H]1COCN1C(=O)OCc2ccccc2

InChI key

XRRRGBIMHQARMF-SNVBAGLBSA-N

form

solid

optical activity

[α]20/D +92°, c = 1 in chloroform

optical purity

ee: 97% (HPLC)

mp

70-74 °C (lit.)

functional group

carboxylic acid
ether
phenyl

Quality Level

Application

Useful chiral synthon (derived from serine) for the asymmetric synthesis of a variety of nitrogen-containing targets.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Falorni, M. et al.
Tetrahedron Asymmetry, 6, 287-287 (1995)

Articles

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

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