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Merck
CN

600148

L-Valine-13C5,15N

98 atom % 15N, 98 atom % 13C, 95% (CP)

Synonym(s):

SILAC Amino Acid, (S)-α-Aminoisovaleric acid-13C5,15N, L-2-Amino-3-methylbutanoic acid-13C5,15N, L-Valine-ul-13C,15N, 13C and 15N Labeled L-valine

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About This Item

Linear Formula:
(13CH3)213CH13CH(15NH2)13CO2H
CAS Number:
202407-30-5
Molecular Weight:
123.10
MDL number:
MFCD00144708
UNSPSC Code:
12352209
PubChem Substance ID:
24881775
NACRES:
NA.12

Key Documents

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isotopic purity

98 atom % 13C
98 atom % 15N

Quality Level

200

Assay

95% (CP)

form

solid

optical activity

[α]25/D +26.6°, c = 1 in 5 M HCl

technique(s)

bio NMR: suitable
protein expression: suitable

mp

295-300 °C (subl.) (lit.)

mass shift

M+6

storage temp.

room temp

SMILES string

[H][13C@]([15NH2])([13CH]([13CH3])[13CH3])[13C](O)=O

InChI

1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1

InChI key

KZSNJWFQEVHDMF-XAFSXMPTSA-N

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Application

L-Valine-13C5,15N is an isotopically labeled amino acid, wherein carbon and nitrogen atoms of L-valine are replaced by 13C5 and 15N isotopes. It can be used as an internal standard in the study of glucose metabolism and the quantitative determination of peptides.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MBBD7373
MBBD7246
MBBC7995
MBBC4485
MBBC4463

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Mass Spectrometric Analysis for the Quality Control of Peptide Conjugate Therapeutics
Peptide Therapeutics (2019)
Jingjing Li et al.
Behavioural brain research, 364, 447-456 (2017-11-09)
Diabetes could negatively affect the structures and functions of the brain, especially could cause the hippocampal dysfunction, however, the potential metabolic mechanism is unclear. The aim of this study was to investigate the changes of glucose metabolism in hippocampus of
Annabell Bachem et al.
Immunity, 51(2), 285-297 (2019-07-06)
Interactions with the microbiota influence many aspects of immunity, including immune cell development, differentiation, and function. Here, we examined the impact of the microbiota on CD8+ T cell memory. Antigen-activated CD8+ T cells transferred into germ-free mice failed to transition into long-lived

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