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Merck
CN

741884

Poly(2-ethyl-2-oxazoline)

average Mn 20,000, PDI <1.4

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About This Item

NACRES:
NA.23
UNSPSC Code:
12162002
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form

solid

Quality Level

mol wt

average Mn 20,000

mp

>300 °C

PDI

<1.4

Application

This Poly(2-ethyl-2-oxazoline) polymer is amorphous and water soluble with good temperature stability. Jordan and coworkers showed biocompatibility, no accumulation in tissue, and rapid clearance from the bloodstream1. End-group modified poly(2-ethyl-2-oxazoline)s have been conjugated to peptides2, and were shown as versatile alternatives to poly(ethylene glycol) (PEG) for both protein and small drug conjugation3.

Potential substitute for poly(vinyl alcohol) and poly(vinyl pyrrolidone). Sometimes it is used as an adhesion promoter in coatings. This is also sometimes used in heat sealing and remoistenable hot-melt adhesives. N-propionyl substituted linear polyethylenimine

Features and Benefits

Nonionic, water-soluble thermoplastic. Better heat stability than poly(vinyl alcohol). Good melt flow, shear stability and Newtonian characteristics. Water is a room temperature Theta solvent.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

PiPrOx-based polymers exhibit diverse stimuli-responsive properties, showcased in recent developments for functional polymer systems.

Microparticles in drug delivery: Study on controlling chitosan microparticle size and distribution, exploring encapsulation of BSA and TPP cross-linker.

The introduction of polymers into the biomedical field has opened new avenues in tissue engineering, implant design, biosensing, and drug delivery.

View All Articles

R. Luxenhofer, M. Lopez-Garcia, A. Frank, H. Kessler, R. Jordan
Polym. Mater. Sci. Eng., 95, 283-284 (2006)
A. Mero, G. Pasut, L. D. Via, M.W. M. Fijten, et al.
J. Controlled Release, 125, 87-95 (2008)
F. C. Gaertner, R. Luxenhofer, B. Blechert, R. Jordan, M. Essler
J. Controlled Release, 119, 291-300 (2007)



Global Trade Item Number

SKUGTIN
741884-5G04061833433034