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746991

Polystyrene-block-poly(acrylic acid)

Synonym(s):

Poly(styrene)-block-poly(acrylic acid), Nanopatterning, block-copolymers

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About This Item

Empirical Formula (Hill Notation):
C4H6N(C8H8)m(C3H4O2)nH
NACRES:
NA.23
UNSPSC Code:
12352100
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form

solid

Quality Level

100

mol wt

Mn 27,000-31,000 (polystyrene), Mn 31,000-37,000 (total), Mn 4,000-6,000 (poly(acrylic acid))

mp

258-263 °C

PDI

≤1.3

Application

Polystyrene-block-polyacrylic acid is a diblock copolymer used for making polymeric vesicles (polymersomes) and other encapsulation applications.1-9 This PS-block-PAA copolymer is 15 wt. % AA; and should form vesicles in water in the 100 nm range. The polystyrene degree of polymerization (DP) is 275 and the polyacrylic acid DP is 50.

Legal Information

Sold for research purposes only.  Not for use in humans.  Before opening or using this product, please read the following terms and conditions.  Use of this product shall constitute acknowledgement and acceptance of these terms and conditions: Use of this product may be covered by one or more of the following US patents and corresponding claims outside the US: 7,714,075; 7,250,479; 7,666,962; 6,642,318; 6,747,111, and pending applications (W2010/8356).  For details contact Aldrich Chemical Company, Inc.

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCC4822

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Articles

Flash NanoPrecipitation (FNP) – Principles and Applications in Medical Imaging and Drug Delivery

Professor Robert K. Prud’homme introduces flash nanoprecipitation (FNP) for nanoparticle fabrication, which is a scalable, rapid mixing process for nanoparticle formulations.

Functional RAFT Polymers for Biomedical Applications

Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.

Polymersomes for Drug Delivery

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.

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Amphiphilic core?shell nanospheres obtained by intramicellar shell crosslinking of polymer micelles with poly(ethylene oxide) linkers
Haiyong Huang,
Chemical Communications (Cambridge, England), 13, 1415-1415 (1998)
Effect of Poly(acrylic acid) Block Length Distribution on Polystyrene-b-Poly(acrylic acid) Aggregates in Solution. 1. Vesicles
Owen Terreau,
Langmuir, 19, 5601-5607 (2003)
Qiang Tian et al.
Langmuir : the ACS journal of surfaces and colloids, 36(17), 4820-4826 (2020-04-11)
The interactions between natural colloidal organic matter and actinides in solutions are complex and not fully understood. In this work, a crew-cut polystyrene-b-poly(acry1ic acid) (PS-b-PAA) micelle is proposed as a model particle for humic acid (HA) colloid with the aim
View All Related Papers

Global Trade Item Number

SKUGTIN
746991-1G04061832891606