913375
Branched polyethylenimine solution
2mg/mL aqueous solution, suitable for biomedical research
Synonym(s):
PEI solution
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About This Item
Linear Formula:
H(NHCH2CH2)mNH2
CAS Number:
MDL number:
UNSPSC Code:
12352116
NACRES:
NA.23
Product Name
Branched polyethylenimine solution, 2mg/mL aqueous solution, suitable for biomedical research
SMILES string
N1CC1
InChI
1S/C2H5N/c1-2-3-1/h3H,1-2H2
InChI key
NOWKCMXCCJGMRR-UHFFFAOYSA-N
form
liquid
concentration
2 mg/mL
color
colorless to pale yellow
storage temp.
2-8°C
Related Categories
Application
High molecular weight branched PEI is commonly used in gene delivery due to its high transfection efficiency in a broad range of cells. Branched PEI has been used to successfully deliver genetic material both in vitro and in vivo, while maintaining low cytotoxicity with DNA complexation.
Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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O Boussif et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(16), 7297-7301 (1995-08-01)
Several polycations possessing substantial buffering capacity below physiological pH, such as lipopolyamines and polyamidoamine polymers, are efficient transfection agents per se--i.e., without the addition of cell targeting or membrane-disruption agents. This observation led us to test the cationic polymer polyethylenimine
W T Godbey et al.
Journal of biomedical materials research, 45(3), 268-275 (1999-07-09)
Poly(ethylenimine) (PEI) samples of various molecular weights and pHs were used to transfect endothelial cells to achieve levels of gene expression for comparison. PEIs with nominal molecular weights of 600, 1200, 1800, 10,000, and 70,000 Da were examined at pHs
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