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Merck
CN

924091

Alkyne-a-TCO

≥95%

别名:

(R,E)-1-(2-(Prop-2-yn-1-yloxy)ethyl)cyclooct-4-en-1-ol, 5-ax-Hydroxy-5-eq-(2-(prop-2-yn-1-yloxy)ethyl)-trans-cyclooctene, Clickable axial 5-hydroxy-trans-cyclooctene

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关于此项目

经验公式(希尔记法):
C13H20O2
分子量:
208.30
UNSPSC Code:
12352200
NACRES:
NA.22
Assay:
≥95%
Form:
viscous liquid
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Quality Segment

assay

≥95%

form

viscous liquid

reaction suitability

reagent type: chemical modification reagent, reagent type: cross-linking reagent
reaction type: click chemistry

color

colorless

functional group

(Alkyne)

storage temp.

−20°C

Application

Alkyne-a-TCO is an axial trans-cyclooctene (a-TCO) for bioconjugation and protein labeling. Alkyne-a-TCO has a CuAAC clickable tag, and the a-TCO reacts rapidly with tetrazines through Diels-Alder reactions, a type of bioorthogonal, copper-free click chemistry. As demonstrated by the Joe Fox lab in Pigga, et al, a-TCOs are more reactive and hydrophilic than standard TCOs, providing favorable physiochemical properties for live-cell and in vivo labeling.

Other new a-TCOs:


存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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