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924113

Amine-a-TCO

Name: Amine-a-TCO
Brand: ALDRICH

别名:

(R,E)-1-(2-Aminoethyl)cyclooct-4-en-1-ol, 5-ax-Hydroxy-5-eq-(2-aminoethyl)-trans-cyclooctene

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关于此项目

经验公式（希尔记法）:

C₁₀H₁₉NO

分子量:

169.26

NACRES:

NA.21

UNSPSC Code:

12352200

Form:

powder or solid (or chunks)

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属性

form

powder or solid (or chunks)

Quality Segment

100

color

white to light yellow

storage temp.

−20°C

说明

Application

Amine-a-TCO is an axial trans-cyclooctene (a-TCO) for bioconjugation and protein labeling. Amine-a-TCO has an acid-reactive terminal amine, and the a-TCO reacts rapidly with tetrazines through Diels–Alder reactions, a type of bioorthogonal, copper-free click chemistry. As demonstrated by the Joe Fox lab in Pigga, et al, a-TCOs are more reactive and hydrophilic than standard TCOs, providing favorable physiochemical properties for live-cell and in vivo labeling.
Other new a-TCOs:

NHS ester-a-TCO (924075)
TAMRA-a-TCO (924083)
Alkyne-a-TCO (924113)

Other Notes

General, Divergent Platform for Diastereoselective Synthesis of trans-Cyclooctenes with High Reactivity and Favorable Physiochemical Properties

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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