933910
Linear polyethylenimine-block-poly(ethylene glycol)
PEG average Mn 5,000, PEI average Mn 30,000
别名:
Nanopatterning, PEG-b-PEI, Poly(ethylene glycol)-block-polyethylenimine, block-copolymers
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关于此项目
线性分子式:
CH3(C2H4O)n(C2H5N)mOH
NACRES:
NA.21
UNSPSC Code:
12352207
form
powder or solid
Quality Segment
mol wt
PEG 5,000 Da, PEG average Mn 5,000, PEI 30,000 Da, PEI average Mn 30,000
color
white to pale yellow
storage temp.
2-8°C
Application
Due to their low immunogenicity profiles, polymeric nonviral vectors have shown promise in advancing the treatment of many severe genetic and acquired diseases via gene therapy.
Poly(ethyleneimine) is one of the most commonly used cationic polymers for gene delivery applications. Copolymers of PEI and hydrophilic poly(ethylene glycol) have been designed to provide a stealth-like shield around polymer/DNA complexes, reducing nonspecific interactions, inhibiting activation of the reticuloendothelial system, and prolonging the half-life of the complexes in the blood.
Poly(ethyleneimine) is one of the most commonly used cationic polymers for gene delivery applications. Copolymers of PEI and hydrophilic poly(ethylene glycol) have been designed to provide a stealth-like shield around polymer/DNA complexes, reducing nonspecific interactions, inhibiting activation of the reticuloendothelial system, and prolonging the half-life of the complexes in the blood.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable