934321
L-Valyl-L-citrulline
≥95%
别名:
L-Valyl-N5-(aminocarbonyl)-L-ornithine, Val-Cit
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关于此项目
经验公式（希尔记法）:
C11H22N4O4
化学文摘社编号:
分子量:
274.32
MDL number:
NACRES:
NA.21
UNSPSC Code:
12352209
Assay:
≥95%
Form:
powder or crystals
Application
This is a cathepsin cleavable linker used in the construction of antibody drug conjugates (ADC & Bioconjugation).
Features and Benefits
Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. The Boc group can be deprotected under acidic conditions to generate a free amine group. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable