940771
TissueFab® PODS Growth Factor Loaded Bioink Kit
Cardiac differentiation, Vis/405 nm
description
Bioburden (Total Aerobic): <5 CFU/ml, Bioburden (fungal): < 5 CFU/mL, Endotoxin: <50 EU/ml
composition
PODS Human Activin A, 25 µg , PODS Human BMP-4, 25 µg , PODS Human FGF-2, 25 µg , PODS Human TGFb-1, 50 million 25 µg , TissueFab® bioink, conductive, Vis/405 nm, low endotoxin
color
black
pH
6.5-7.5
viscosity
2-20 cP(37 °C)
compatibility
(extrusion-based 3D bioprinting)
storage temp.
−20°C
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General description
Rethink your bioinks with TissueFab®
About the material:
The TissueFab PODS Growth Factor Loaded Bioink Kit, cardiac differentiation, Vis/405 nm contains:
Suitable for extrusion-based bioprintingVisible light crosslinking at 405 nm wavelength
TissueFab PODS Growth Factor Loaded Bioink kit, cardiac differentiation, conductive Vis/405nm is a ready-to-use bioink kit which is formulated for high cell viability, printing fidelity, and is designed for extrusion-based 3D bioprinting and subsequent crosslinking with exposure to 405nm visible light. TissueFab PODS Growth Factor Loaded Bioink kit, cardiac differentiation, conductive Vis/405nm can be used with most extrusion-based bioprinters, is biodegradable and cytocompatible. The included bioink component is an electrically conductive bioink for 3D bioprinting applications. It is intended to generate ideal cell environments for cardiac cells, which enable them to transfer electrical signals, enhancing cell communication and capacity for network formation. It is based on gelatin methacryloyl (GelMA) hydrogel system.Carbon nanotubes (CNTs) are incorporated to introduce conductivity, meanwhile enhance the mechanical properties of GelMA hydrogels.
Included growth facors, FGF-2, BMP-4, Activin A, and TGFb-1 are known to play crucial roles in regulating cardiac differentiation or promoting cardiac cell survival. Their inclusion with PODS® delivery system allows their sustained release within bioprinted constructs and retainment of 70% bioactivity after 6 months. When mixed with the bioink component, the included PODS growth factors can promote cardiac cell differentiation. More information and a step by step protocol can be found under the
"More Documents" section of this page.
About the material:
The TissueFab PODS Growth Factor Loaded Bioink Kit, cardiac differentiation, Vis/405 nm contains:
- Low endotoxin conductive bioink containing visible light photoinitiator
- Human FGF-2 PODS
- Human BMP-4 PODS
- Human Activin A PODS
- Human TGFb-1 PODS
Suitable for extrusion-based bioprintingVisible light crosslinking at 405 nm wavelength
TissueFab PODS Growth Factor Loaded Bioink kit, cardiac differentiation, conductive Vis/405nm is a ready-to-use bioink kit which is formulated for high cell viability, printing fidelity, and is designed for extrusion-based 3D bioprinting and subsequent crosslinking with exposure to 405nm visible light. TissueFab PODS Growth Factor Loaded Bioink kit, cardiac differentiation, conductive Vis/405nm can be used with most extrusion-based bioprinters, is biodegradable and cytocompatible. The included bioink component is an electrically conductive bioink for 3D bioprinting applications. It is intended to generate ideal cell environments for cardiac cells, which enable them to transfer electrical signals, enhancing cell communication and capacity for network formation. It is based on gelatin methacryloyl (GelMA) hydrogel system.Carbon nanotubes (CNTs) are incorporated to introduce conductivity, meanwhile enhance the mechanical properties of GelMA hydrogels.
Included growth facors, FGF-2, BMP-4, Activin A, and TGFb-1 are known to play crucial roles in regulating cardiac differentiation or promoting cardiac cell survival. Their inclusion with PODS® delivery system allows their sustained release within bioprinted constructs and retainment of 70% bioactivity after 6 months. When mixed with the bioink component, the included PODS growth factors can promote cardiac cell differentiation. More information and a step by step protocol can be found under the
"More Documents" section of this page.
Application
- cardiac differentiation
- cell culture
- tissue engineering
Features and Benefits
Key Features and Benefits:
Each TissueFab® bioink is developed and tested to meet strict criteria to best suit researchers′ needs. This includes:
Each TissueFab® bioink is developed and tested to meet strict criteria to best suit researchers′ needs. This includes:
- Printability and rheological properties
- Crosslinking
- Cell viability Biocompatibility
- Low bioburden
- Low endotoxin
Legal Information
PODS is a registered trademark of Cell Guidance Systems Ltd
TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany
Kit Components Also Available Separately
Product No.
Description
SDS
Storage Class
10 - Combustible liquids
wgk
WGK 3
Regulatory Information
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Find documentation for the products that you have recently purchased in the Document Library.
The Multifunctional Contribution of FGF Signaling to Cardiac Development, Homeostasis, Disease and Repair
Khosravi F,et.al
Frontiers in Cell and Developmental Biology, 9 (2021)
Activin A and BMP4 Signaling for Efficient Cardiac Differentiation of H7 and H9 Human Embryonic Stem Cells
Sa S,et.al
Journal of stem cells & regenerative medicine, 8, 198-202 (2012)
TGF-beta1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro
Goumans MJ, et.al
Stem Cell Research, 1, 138-149 (2007)
Carbon-nanotube-embedded hydrogel sheets for engineering cardiac constructs and bioactuators
Shin SR,et.al
ACS Nano, 7, 2369?2380-2369?2380 (2013)
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